|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 185 and 404 of Human GSDMD|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-30824 targets GSDMD in WB applications and shows reactivity with Human samples.
The PA5-30824 immunogen is recombinant fragment corresponding to a region within amino acids 185 and 404 of Human GSDMD.
Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described.
Protein Aliases: DF5L; DFNA5L; gasdermin domain containing 1; Gasdermin domain-containing protein 1; Gasdermin-D; GSDMDC1
Gene Aliases: DF5L; DFNA5L; FKSG10; GSDMD; GSDMDC1
UniProt ID: (Human) P57764
Entrez Gene ID: (Human) 79792