|Immunocytochemistry (ICC)||2 µg/ml|
|Immunofluorescence (IF)||2 µg/ml|
|Western Blot (WB)||1-3 µg/ml|
|Western Blot (WB)||See 2 publications below|
|Tested Species reactivity||Bovine, Guinea pig, Human, Mouse, Rat|
|Published species reactivity||Rat Human|
|Host / Isotype||Mouse / IgG2b|
|Immunogen||Partially purified rat brain Galphai1 protein|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage conditions||4° C|
MA5-12800 targets Galphai1 G-Protein in WB applications and shows reactivity with Bovine, Guinea Pig, Human, mouse, and Rat samples.
The MA5-12800 immunogen is partially purified rat brain Galphai1 protein.
GTP-binding proteins (G-proteins) play a critical role in signal transduction by coupling receptors to effectors. The intracellular consequences of G-protein activation include second messenger generation, protein phosphorylation, ion channel activation, gene induction, cell growth, and differentiation. Gi belongs to the pertussis toxin sensitive G-proteins. Gi consists of three different subtypes of alpha-subunits (alphai1, alphai2 and alphai3)
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Adenylate cyclase-inhibiting G alpha protein; Gi1 protein alpha subunit; Gi1 protein alpha-subunit; guanine nucleotide binding protein (G protein), alpha inhibiting 1; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1; guanine nucleotide binding protein, alpha inhibiting 1; Guanine nucleotide-binding protein G(i) subunit alpha-1; guanine nucleotide-binding protein G(i), alpha-1 subunit
Gene Aliases: AU046200; BOS_4157; BPGTPB; Gi; Gialpha1; Gnai-1; GNAI1
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