|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 136 and 355 of Human Glucosidase I|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-28312 targets Glucosidase I in WB applications and shows reactivity with Human samples.
The PA5-28312 immunogen is recombinant fragment corresponding to a region within amino acids 136 and 355 of Human Glucosidase I.
This gene encodes the first enzyme in the N-linked oligosaccharide processing pathway. The enzyme cleaves the distal alpha-1,2-linked glucose residue from the Glc(3)-Man(9)-GlcNAc(2) oligosaccharide precursor. This protein is located in the lumen of the endoplasmic reticulum. Defects in this gene are a cause of type IIb congenital disorder of glycosylation (CDGIIb). Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CDG2B; GCS1; glucosidase I; Mannosyl-oligosaccharide glucosidase; Processing A-glucosidase I
Gene Aliases: CDG2B; CWH41; DER7; GCS1; MOGS
UniProt ID: (Human) Q13724
Entrez Gene ID: (Human) 7841
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