|Immunohistochemistry (Paraffin) (IHC (P))||Assay-Dependent|
|Western Blot (WB)||0.5 µg/ml|
|Tested Species reactivity||Human, Non-human primate, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Full length human GPX3 protein expressed in E. coli.|
|Storage buffer||whole serum|
|Contains||0.1% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
The target sequence has 89% sequence homology with mouse, 88% sequence homology with bovine and 84% sequence homology with porcine.
Suggested positive control: HeLa whole cell extract.
GPX3 (Glutathione Peroxidase 3) belongs to the glutathione peroxidase family. It protects cells and enzymes from oxidative damage by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide by glutathione. There is increasing evidence that GPX3 is a novel tumor suppressor and a therapeutic target for insulin resistance and diabetes mellitus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Extracellular glutathione peroxidase; Glutathione peroxidase 3; glutathione peroxidase 3 (plasma); GPx-3; GPx-P; GSHPx-3; GSHPx-P; Plasma glutathione peroxidase
Gene Aliases: GPx-3; GPx-P; GPX3; GPXP; GSHPx-3; GSHPx-P
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