|Immunohistochemistry (Paraffin) (IHC (P))||10 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 20 amino acid peptide from internal region of human PYGB.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
BLAST analysis of the peptide immunogen showed homology with the following human proteins: PYGL (100%), PYGB (100%), PYGM (100%).
In IHC applications, antigen retrieval using a citrate buffer (pH 6.0) is recommended.
The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: glycogen phosphorylase B; Glycogen phosphorylase brain form; Glycogen phosphorylase, brain form
Gene Aliases: GPBB; PYGB
UniProt ID: (Human) P11216
Entrez Gene ID: (Human) 5834
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