|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 378-408 amino acids from the C-terminal region of human HABP2|
|Purification||Size-exclusion - Dialysis, Ammonium sulfate precipitation|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
HABP2 is an extracellularserine protease that binds hyaluronic acid and is involved in celladhesion. The encoded protein is synthesized as a single chain, butthen undergoes an autoproteolytic event to form the functionalheterodimer. Further autoproteolysis leads to smaller, inactivepeptides. This protease is known to cleave urinary plasminogenactivator, coagulation factor VII, and the alpha and beta chains offibrinogen, but not prothrombin, plasminogen, or the gamma chain offibrinogen. Two transcript variants encoding different isoformshave been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Factor seven-activating protease; factor VII activating protein; Factor VII-activating protease; FSAP; HABP; Hepatocyte growth factor activator-like protein; HGFAL; hyaduronic acid-binding protein 2; Hyaluronan-binding protein 2; hyaluronic acid binding protein 2; PHBP; plasma hyalurona; plasma hyaluronan binding protein; Plasma hyaluronan-binding protein
Gene Aliases: AI035669; FSAP; HABP; HABP2; HGFAL; NMTC5; PHBP
Molecular Function: annexin calcium-binding protein calmodulin enzyme modulator hydrolase intracellular calcium-sensing protein peptide hormone protease protease inhibitor receptor serine protease signaling molecule
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