|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 49-78 amino acids from the N-terminal region of human HARS|
|Purification||Size-exclusion - Dialysis, Ammonium sulfate precipitation|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with bovine and mouse based on sequence homology.
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. HARS is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. This enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The protein is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: HARS; HisRS; histidine translase; Histidine--tRNA ligase, cytoplasmic; Histidyl-tRNA synthetase; Histidyl-tRNA synthetase, cytoplasmic; HRS
Gene Aliases: CMT2W; HARS; HRS; USH3B
UniProt ID: (Human) P12081
Entrez Gene ID: (Human) 3035
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