|Flow Cytometry (Flow)||1:10-1:50|
|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 131-156 amino acids from the N-terminal region of human HCK|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with mouse, non-human primate and rat based on sequence homology.
HCK is a member of the Srcfamily of tyrosine kinases. This protein is primarily hemopoietic,particularly in cells of the myeloid and B-lymphoid lineages. Itmay help couple the Fc receptor to the activation of therespiratory burst. In addition, it may play a role in neutrophilmigration and in the degranulation of neutrophils. Multipleisoforms with different subcellular distributions are produced dueto both alternative splicing and the use of alternative translationinitiation codons, including a non-AUG (CUG) codon.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Hematopoietic cell kinase; Hemopoietic cell kinase; JTK9; p59-HCK/p60-HCK; p59Hck; p61Hck; Tyrosine-protein kinase HCK
Gene Aliases: HCK; JTK9; p59Hck; p61Hck
UniProt ID: (Human) P08631
Entrez Gene ID: (Human) 3055
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