|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 263 and 504 of Human HELIOS|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-30444 targets HELIOS in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-30444 immunogen is recombinant fragment corresponding to a region within amino acids 263 and 504 of Human HELIOS.
This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This protein forms homo- or hetero-dimers with other Ikaros family members, and is thought to function predominantly in early hematopoietic development. Multiple transcript variants encoding different isoforms have been found for this gene, but the biological validity of some variants has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 2 (Helios); HELIOS; IKAROS family zinc finger 2 (Helios); Ikaros family zinc finger protein 2; subfamily 1A; zinc finger DNA binding protein Helios; zinc finger protein; Zinc finger protein Helios; zinc finger protein, subfamily 1A, 2 (Helios); ZNF1A2; ZNFN1A2
Gene Aliases: ANF1A2; HELIOS; IKZF2; ZNF1A2; ZNFN1A2
UniProt ID: (Human) Q9UKS7
Entrez Gene ID: (Human) 22807
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