|Western Blot (WB)||1-3 ug/ml|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (AANLSRNGPALQE) corresponding to the N-terminus amino acids of DBNL|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is expected to recognize all reported isoforms (NP_054782.2; NP_001014436.1; NP_001116428.1).
It is predicted to react with canine and rat based on sequence homology.
Actin-binding adapter protein. May act as a common effector of antigen receptor-signaling pathways in leukocytes. Its association with dynamin suggests that it may also connect the actin cytoskeleton to endocytic function. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes. Binds to F-actin but is not involved in actin polymerization, capping or bundling. Does not bind G-actin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Actin-binding protein 1; Cervical mucin-associated protein; Cervical SH3P7; DBNL; drebrin F; Drebrin-F; drebrin-like; Drebrin-like protein; HIP-55; HIP-55 protein; HPK1-interacting protein of 55 kDa; SH3 domain-containing protein 7; SH3P7; src homology 3 domain-containing protein HIP-55
Gene Aliases: ABP1; CMAP; DBNL; HIP-55; HIP55; mAbp1; PP5423; SH3P7
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