|ELISA (ELISA)||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
|Tested Species reactivity||Virus|
|Host / Isotype||Goat / IgG|
|Immunogen||Purified native gp120 from strain IIIB.|
|Storage buffer||PBS, pH 7.2|
|Contains||0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C|
PA1-7218 detects the HIV1 gp120. This antibody does not cross-react with human T or B cells.
PA1-7218 has been successfully used in Western blot and ELISA procedures.
The PA1-7218 immunogen is purified native gp120 from strain IIIB.
Recommended storage of up to 6 months at 2-8°C. For long term storage, aliquot and freeze. avoiding freeze/thaw cycles.
Human immunodeficiency virus type 1 (HIV-1) entry into target cells is directed by the envelope (Env) glycoproteins, which are present on the surface of HIV-1 virion or infected cells in the form of trimers consisting of gp120/gp41 complexes. The surface subunit, gp120, initiates the entry process by interacting sequentially with the CD4 receptor and a co-receptor CCR5 or CXCR4, thereby inducing a conformational change that allows the transmembrane (TM) gp41 subunit to mediate fusion between viral and target cell membranes. Cleavage of Env into its gp120 and gp41 components is necessary for activation of its fusogenic activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: HIV Glycoprotein 120; HIV-1 Glycoprotein 120; Human immunodeficiency virus
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