|Western Blot (WB)||1:1000-1:5000|
|Tested Species reactivity||Virus|
|Host / Isotype||Rat / IgG1|
|Immunogen||TrpE-Fusion protein produced in X63Ag8.653 cells|
|Contains||0.1% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
MA5-17015 recognizes HIV-2 Nef and does not cross react with HIV-1 Nef.
MA5-17015 has been successfully used in immunoprecipitation and Western blot applications.
The MA5-17015 immunogen is a TrpE-Fusion protein produced in X63Ag8.653 cells.
Nef is a multifunctional protein of 27 kDa in HIV1 and 35 kDa in HIV2. It induces the endocytosis of CD4 Receptor and reduces the MHC1 Receptors. Nef enhances viral infectivity and affects T-cell signalling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: F-protein; HIV-2; HIV-2 nef; HIV2 nef protein; Human immunodeficiency virus 2 nef; Nefprotein; Negative factor
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