|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:200|
|Western Blot (WB)||1:500-1:1000|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to amino acids 180-220 of human Hox-A1|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.2|
|Contains||0.05% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
This antibody detects endogenous protein at a molecular weight of 37 kDa.
Purity is >95% by SDS-PAGE.
Hox genes play a fundamental role in the development of the vertebrate central nervous system, heart, axial skeleton, limbs, gut, urogenital tract and external genitalia. The homeobox gene HoxA1 is transcriptionally regulated by retinoic acid (RA) and encodes a transcription factor which has been shown to play important roles in cell differentiation and embryogenesis. HoxA1 is also expressed in cancers, such as mammary tumors, though it is not expressed in normal gland or in precancerous mammary tissues. At embryonic stages, HoxA2 is expressed in the mesenchyme and epithelial cells of the palate, however its expression is restricted to the tips of the growing palatal shelves.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: early retinoic acid 1; homeo box A1; homeobox 1F; homeobox protein Hox-1.6; Homeobox protein Hox-1F; Homeobox protein Hox-A1; homeoboxless protein ERA-1-399; homeotic protein ERA-1-993; Hox 1.6-like protein; HOX A1 homeodomain protein; HOX1F; HOXA1; lab-like protein
Gene Aliases: BSAS; ERA1; Hox-1.6; HOX1; HOX1F; HOXA1
UniProt ID: (Human) P49639
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