|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 33 and 281 of Human HPS2|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-29858 targets HPS2 in WB applications and shows reactivity with Human samples.
The PA5-29858 immunogen is recombinant fragment corresponding to a region within amino acids 33 and 281 of Human HPS2.
This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is part of the heterotetrameric AP-3 protein complex which interacts with the scaffolding protein clathrin. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: adapter-related protein complex 3 subunit beta-1; Adaptor protein complex AP-3 subunit beta-1; adaptor related protein complex 3, beta 1 subunit; Adaptor-related protein complex 3 subunit beta-1; adaptor-related protein complex 3, beta 1 subunit; ADTB3; ADTB3A; AP-3 complex beta-3A subunit; AP-3 complex subunit beta-1; Beta-3A-adaptin; beta3A-adaptin; Clathrin assembly protein complex 3 beta-1 large chain; HPS2
Gene Aliases: ADTB3; ADTB3A; AP3B1; HPS; HPS2; PE
UniProt ID: (Human) O00203
Entrez Gene ID: (Human) 8546
Molecular Function: membrane traffic protein
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