|Western Blot (WB)||1:5000-1:20,000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 166 and 369 of Human HIP|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-31630 targets HIP in WB applications and shows reactivity with Human samples.
The PA5-31630 immunogen is recombinant fragment corresponding to a region within amino acids 166 and 369 of Human HIP.
The protein encoded by this gene is an adaptor protein that mediates the association of the heat shock proteins HSP70 and HSP90. This protein has been shown to be involved in the assembly process of glucocorticoid receptor, which requires the assistance of multiple molecular chaperones. The expression of this gene is reported to be downregulated in colorectal carcinoma tissue suggesting that is a candidate tumor suppressor gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AAG2; Aging-associated protein 2; FAM10A1; heat shock 70kD protein binding protein; HIP; Hsc70-interacting protein; Hsp70-interacting protein; Progesterone receptor-associated p48 protein; Protein FAM10A1; Putative tumor suppressor ST13; Renal carcinoma antigen NY-REN-33; SNC6; Suppression of tumorigenicity 13 protein; testis secretory sperm-binding protein Li 233m
Gene Aliases: AAG2; FAM10A1; FAM10A4; HIP; HOP; HSPABP; HSPABP1; P48; PRO0786; SNC6; ST13
UniProt ID: (Human) P50502
Entrez Gene ID: (Human) 6767
Molecular Function: chaperone
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