|Western Blot (WB)||0.3-2 ug/ml|
|Western Blot (WB)||See 1 publications below|
|Tested Species reactivity||Human|
|Published species reactivity||Mouse|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (CTSYNMDRFINK) corresponding to the C-terminus amino acids of HSD11B1|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with bovine based on sequence homology.
The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Two transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 11-beta-HSD1; 11-beta-hydroxysteroid dehydrogenase 1; 11-DH; Corticosteroid 11-beta-dehydrogenase isozyme 1; HDL; HSD11; HSD11B; HSD11B1; HSD11L; hydroxysteroid (11-beta) dehydrogenase 1; MGC13539; OTTHUMP00000034650; SDR26C1; Short chain dehydrogenase/reductase family 26C member 1; short chain dehydrogenase/reductase family 26C, member 1
Gene Aliases: 11-beta-HSD1; 11-DH; CORTRD2; HDL; HSD11; HSD11B; HSD11B1; HSD11L; SDR26C1
UniProt ID: (Human) P28845
Entrez Gene ID: (Human) 3290
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