|Flow Cytometry (Flow)||1:10-1:50|
|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 89-118 amino acids from the central region of human HSD17B3|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 17-beta-HSD 3; 17-beta-HSD3; 17-beta-hydroxysteroid dehydrogenase type 3; EDH17B3; hydroxysteroid (17-beta) dehydrogenase 3; hydroxysteroid dehydrogenase 3; member 2; SDR12C2; short chain dehydrogenase/reductase family 12C; Short chain dehydrogenase/reductase family 12C member 2; short chain dehydrogenase/reductase family 12C, member 2; Testicular 17-beta-hydroxysteroid dehydrogenase; Testosterone 17-beta-dehydrogenase 3
Gene Aliases: EDH17B3; HSD17B3; SDR12C2
UniProt ID: (Human) P37058
Entrez Gene ID: (Human) 3293
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