|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Immunohistochemistry (IHC)||See 1 publications below|
|Tested Species reactivity||Human|
|Published species reactivity||Pig|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 122 and 310 of Human HSD17B3|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-30063 targets HSD17B3 in IHC (P), ICC, IF and WB applications and shows reactivity with Human samples.
The PA5-30063 immunogen is recombinant fragment corresponding to a region within amino acids 122 and 310 of Human HSD17B3.
This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 17-beta-HSD 3; 17-beta-HSD3; 17-beta-hydroxysteroid dehydrogenase type 3; EDH17B3; hydroxysteroid (17-beta) dehydrogenase 3; hydroxysteroid dehydrogenase 3; member 2; SDR12C2; short chain dehydrogenase/reductase family 12C; Short chain dehydrogenase/reductase family 12C member 2; short chain dehydrogenase/reductase family 12C, member 2; Testicular 17-beta-hydroxysteroid dehydrogenase; Testosterone 17-beta-dehydrogenase 3
Gene Aliases: EDH17B3; HSD17B3; SDR12C2
UniProt ID: (Human) P37058
Entrez Gene ID: (Human) 3293
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