|ELISA (ELISA)||Assay dependent|
|Flow Cytometry (Flow)||1/100|
|Immunofluorescence (IF)||Assay dependent|
|Immunoprecipitation (IP)||Assay dependent|
|Western Blot (WB)||1 µg/ml|
|Western Blot (WB)||See 44 publications below|
|Miscellaneous PubMed (MISC)||See 4 publications below|
|Immunocytochemistry (ICC)||See 57 publications below|
|Flow Cytometry (Flow)||See 3 publications below|
|ELISA (ELISA)||See 2 publications below|
|Immunohistochemistry (IHC)||See 4 publications below|
|Tested Species reactivity||Virus|
|Published species reactivity||Virus , Human , Mouse|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified HCV core-GST fusion protein (genotype 1b).|
|Contains||0.05% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
MA1-080 detects hepatitis C virus (HCV) core protein from transfected human and primate cell lines.
MA1-080 has been successfully used in Western blot, immunoprecipitation, immunofluorescence and ELISA procedures. By Western blot, this antibody detects a single ~21 kDa protein representing HCV core protein in various transfected cell lines. Immunofluorescence staining of HCV core protein in transfected chimp hepatocytes yields a staining pattern consistent with cytoplasmic and vesicular staining.
The MA1-080 immunogen is purified HCV core-GST fusion protein (genotype 1b). This antibody recognizes an epitope between amino acid residues 21-40 of HCV core protein. This sequence is conserved among different HCV strains.
Hepatitis C virus (HCV) is the primary cause of non-A, non-B hepatitis and results in most HCV-infected people developing chronic infections, liver cirrhosis and hepatocellular carcinoma. The ~21 kDa core protein of HCV is well conserved among different HCV genotypes and may suppress hepatitis B virus replication in a phosphorylation dependent manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: HCV core; HepC; HepC core
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