|ELISA (ELISA)||1-10 µg/ml|
|Western Blot (WB)||1-10 µg/ml|
|Miscellaneous PubMed (MISC)||See 1 publications below|
|Tested Species reactivity||Human|
|Published species reactivity||Not Applicable|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified high molecular weight kininogen.|
|Storage buffer||PBS, pH 7.4|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
MA1-10832 detects High MW Kininogen, heavy chain, from human samples.
MA1-10832 has been successfully used in ELISA and Western blot applications.
The MA1-10832 immunogen is purified high molecular weight kininogen.
This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Alpha-2-thiol proteinase inhibitor; bradykinin; Fitzgerald factor; High molecular weight kininogen; HMWK; HMWK-kallikrein factor; Kininogen-1; Williams-Fitzgerald-Flaujeac factor
Gene Aliases: BDK; BK; KNG; KNG1
UniProt ID: (Human) P01042
Entrez Gene ID: (Human) 3827
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