|ELISA (ELISA)||Assay Dependent|
|Immunocytochemistry (ICC)||4 ug/ml|
|Immunoprecipitation (IP)||Assay Dependent|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG2b|
|Immunogen||Human Hydroxymethylglutaryl-CoA lyase|
|Storage buffer||HEPES buffered saline|
|Contains||0.02% sodium azide|
|Storage conditions||4° C|
The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 3-hydroxy-3-methylglutarate-CoA lyase; 3-hydroxy-3-methylglutaryl-CoA lyase; 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase; HL; HMG-CoA lyase; hydroxymethylglutaricaciduria; hydroxymethylglutaryl-CoA lyase; Hydroxymethylglutaryl-CoA lyase, mitochondrial; mitochondrial; mitochondrial 3-hydroxy-3-methylglutary; mitochondrial 3-hydroxy-3-methylglutaryl-CoA lyase
Gene Aliases: HL; HMGCL
UniProt ID: (Human) P35914
Entrez Gene ID: (Human) 3155
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