|ELISA (ELISA)||Assay dependent.|
|Immunohistochemistry (Frozen) (IHC (F))||1:10|
|Immunoprecipitation (IP)||Assay dependent.|
|Western Blot (WB)||1:10|
|Tested Species reactivity||Human, Non-human primate|
|Host / Isotype||Rabbit / IgG|
|Storage buffer||PBS with 0.1% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||4° C|
Human CD54, also known as intercellular adhesion molecule-1 (ICAM1), is a 85-110 kDa single-chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. It shares considerable amino acid sequence homology with CD50 (ICAM3) and with CD102 (ICAM2). ICAM1 (CD54) is expressed by activated endothelial cells. It is detected on cells of many other lineages (e.g. epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils, with lower levels that increase in inflammation. Also, ICAM1 (CD54) is detected in some carcinoma and melanoma cells. Soluble ICAM1 (CD54) is detectable in the plasma and is elevated in patients with various inflammatory syndromes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BB2; CD54; cell surface glycoprotein P3.58; human rhinovirus receptor; ICAM-1; Intercellular adhesion molecule 1; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; Major group rhinovirus receptor; P3.58
Gene Aliases: BB2; CD54; ICAM1; P3.58
UniProt ID: (Human) P05362
Entrez Gene ID: (Human) 3383
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