|Tested Species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (ESPAEGEVFAIQ) corresponding to the C-terminus amino acids of ICAM5|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with bovine, mouse, porcine and rat based on sequence homology.
The protein encoded by this gene is a member of the intercellular adhesion molecule family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ICAM-5; ICAM5; Intercellular adhesion molecule 5; intercellular adhesion molecule 5, telencephalin; Telencephalin; TLCN; TLN
Gene Aliases: ICAM5; TLCN; TLN
UniProt ID: (Human) Q9UMF0
Entrez Gene ID: (Human) 7087
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