|ELISA (ELISA)||2 µg/ml|
|Neutralization (Neu)||10-40 µg/ml|
|Western Blot (WB)||1-2 ug/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Recombinant, full length human protein.|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
MA1-24775 detects IGFBP1 from human samples.
MA1-24775 has been successfully used in neutralization, ELISA , and Western blot procedures. The Neutralization Dose50 (ND50) for this antibody is 10-40 ug/ml in the presence of approximately 5 ug/ml of recombinant human IGFBP1 and approximately 6 ng/mL of recombinant human IGF1, using human MCF7 cells.
The MA1-24775 immunogen is recombinant, full length human protein.
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AFBP; alpha-pregnancy-associated endometrial globulin; amniotic fluid binding protein; binding protein-25; binding protein-26; binding protein-28; growth hormone independent-binding protein; hIGFBP-1; IBP-1; IBP1; IGF-binding protein 1; IGF-BP25; IGFBP-1; insulin-like growth factor binding protein 1; Insulin-like growth factor-binding protein 1; Placental protein 12; PP12
Gene Aliases: AFBP; hIGFBP-1; IBP1; IGF-BP25; IGFBP1; PP12
UniProt ID: (Human) P08833
Entrez Gene ID: (Human) 3484
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