Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
PA1-21991 detects IGFBP2 in bovine, hamster, equine, goat, human, mouse and non-human primate samples. This antibody may show a slight cross reactivity with IGFBP 1, 3, 4, & 5.
PA1-21991 has been successfully used in Immunoprecipitation and Western Blot procedures.
The PA1-21991 immunogen is bovine IGFBP 2 purified by immunoaffinity and HPLC chromatographies from conditioned medium of Madin Darby Bovine Kidney cells.
IGFBP2 (insulin-like growth factor binding protein 2) is a member of the ISGBP family which bind various IGFs. IGFBP2 is overexpressed in a wide spectrum of cancers, including glioma, prostate cancer, synovial sarcoma, neuroblastoma, colon cancer, adrenocortical cancer, lung cancer, Wilms' tumor, and hepatoblastoma. The overexpression of IGFBP2 also correlates with the aggressiveness of some tumors. IGFBP2 activates the expression of matrix metalloprotease 2, which contributes to cell invasiveness.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: IBP-2; IGF binding protein 2; IGF-binding protein 2; IGFBP; IGFBP-2; Insulin like growth factor binding protein; insulin-like growth factor binding protein 2; insulin-like growth factor binding protein 2, 36kDa; Insulin-like growth factor-binding protein 2; OTTHUMP00000207753
Gene Aliases: BP2; IBP2; Igfbp-2; IGFBP2
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support