|Immunohistochemistry (Paraffin) (IHC (P))||15 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 15 amino acid peptide from internal region of human IGSF8.|
|Contains||< 0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
In IHC applications, antigen retrieval using HIER and sodium citrate (pH 6.0) is recommended.
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Bovine, Bat, Elephant, Panda, Rabbit, Pig (100%) Mouse, Rat (93%).
This gene encodes a member the EWI subfamily of the immunoglobulin protein superfamily. Members of this family contain a single transmembrane domain, an EWI (Glu-Trp-Ile)-motif and a variable number of immunoglobulin domains. This protein interacts with the tetraspanins CD81 and CD9 and may regulate their role in certain cellular functions including cell migration and viral infection. The encoded protein may also function as a tumor suppressor by inhibiting the proliferation of certain cancers. Alternate splicing results in multiple transcript variants that encode the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD316; CD81 partner 3; CD81P3; EWI-2; EWI2; Glu-Trp-Ile EWI motif-containing protein 2; IgSF8; Immunoglobulin superfamily member 8; immunoglobulin superfamily, member 8; KCT-4; Keratinocytes-associated transmembrane protein 4; LIR-D1; PGRL; Prostaglandin regulatory-like protein
Gene Aliases: CD316; CD81P3; EWI-2; EWI2; IGSF8; KCT-4; KCT4; LIR-D1; PGRL
UniProt ID: (Human) Q969P0
Entrez Gene ID: (Human) 93185
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.