|Western Blot (WB)||1:1500-1:2500|
|Tested Species reactivity||Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein - full length mouse IkB alpha protein|
|Storage buffer||PBS, pH 7.2|
|Contains||0.1% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
PA1-28845 detects IKB alpha from mouse samples.
PA1-28845 has been successfully used in Western blot applications.
The PA1-28845 immunogen is recombinant protein - full length mouse IkB alpha protein.
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
IKBa protein is a NF-kB inhibitory protein. It binds NF-kB, retains the complex in the cytoplasm, prevents it from entering nuclear and functioning as a transcription factor. Upon receiving a variety of signals, IKBa undergoes phosphorylation at serine residues by a ubiquitin-dependent protein kinases and finally degraded by the proteasome. Free NF-kB then binds to DNA and affects gene expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: I(Kappa)B(alpha); I-kappa-B-alpha; I-kappaBalpha; ikappaBalpha; IkB-alpha; NF-kappa-B inhibitor alpha; nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha; nuclear factor of kappa light polyp gene enhancer in B-cell 1; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
Gene Aliases: AI462015; Ikba; Nfkbi; Nfkbia
UniProt ID: (Mouse) Q9Z1E3
Entrez Gene ID: (Mouse) 18035
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