|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 768 and 1055 of Human IKBKAP|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-29112 targets IKBKAP in IF and WB applications and shows reactivity with Human samples.
The PA5-29112 immunogen is recombinant fragment corresponding to a region within amino acids 768 and 1055 of Human IKBKAP.
The protein encoded by this gene is a scaffold protein and a regulator for 3 different kinases involved in proinflammatory signaling. This encoded protein can bind NF-kappa-B-inducing kinase (NIK) and IKKs through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DYS; elongator acetyltransferase complex subunit 1; Elongator complex protein 1; ELP1; FD; IKAP; IkappaB kinase complex-associated protein; IKI3; IKK complex-associated protein; IKK-complex-associated protein IKAP; inhibitor of kappa light polypeptide enhancer in B-cells, kinase complex-associated protein; p150; TOT1
Gene Aliases: 3110040G09Rik; 6030413P05; C78473; DYS; ELP1; FD; IKAP; IKBKAP; IKI3; TOT1
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