|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 76-103 amino acids from the central region of human IKZF3|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with bovine based on sequence homology.
This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 3 (Aiolos); AIO; AIOLOS; IKAROS family zinc finger 3 (Aiolos); Ikaros family zinc finger protein 3; subfamily 1A; zinc finger DNA binding protein Aiolos; zinc finger protein; Zinc finger protein Aiolos; zinc finger protein, subfamily 1A, 3 (Aiolos); ZNFN1A3
Gene Aliases: 5830411O07Rik; AIO; AIOLOS; IKZF3; Zfpn1a3; ZNFN1A3
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