|ELISA (ELISA)||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
|Western Blot (WB)||See 1 publications below|
|ELISA (ELISA)||See 9 publications below|
|Blocking Assay (BLOCK)||See 5 publications below|
|Miscellaneous PubMed (MISC)||See 1 publications below|
|Tested Species reactivity||Mouse|
|Published species reactivity||Mouse|
|Host / Isotype||Rat / IgG2a|
|Immunogen||Recombinant mouse IL-12(p70) (CHO cell-derived)|
MM121 targets IL-12 in ELISA and WB applications and shows reactivity with mouse samples.
The MM121 immunogen is recombinant mouse IL-12(p70) (CHO cell-derived).
MM121 detects IL-12 which has a predicted molecular weight of approximately 22 kDa.
This antibody is produced by injecting Rat IgG secreting hybridoma cells into the peritoneum of mice. The resulting ascites is collected from the mice and the antibody is purified.
This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CLMF p35; CLMF p40; Cytotoxic lymphocyte maturation factor 35 kDa subunit; Cytotoxic lymphocyte maturation factor 40 kDa subunit; IL-12 subunit p35; IL-12 subunit p40; IL-12A; IL-12B; IL12p35; IL12P40; interleukin 12a p35 subunit; Interleukin-12 subunit alpha; Interleukin-12 subunit beta
Gene Aliases: Il-12a; Il-12b; IL-12p35; Il-12p40; Il12a; Il12b; Il12p40; Ll12a; p35; p40
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