|ELISA (ELISA)||Assay Dependent|
|Tested Species reactivity||Human|
|Host / Isotype||Rat / IgG|
|Immunogen||Recombinant human IL-13|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is specific for natural and recombinant IL-13. The unlabeled version of this antibody does not perform as a detection antibody with secondary reagents in Western blot, however the biotinylated version, Product # M130B, was successfully tested as a detection antibody in a sandwich ELISA with Product # P130E.
Endotoxin level <0.52 EU/mg.
This antibody is produced by injecting Rat IgG secreting hybridoma cells into the peritoneum of mice. The resulting ascites is collected from the mice and the antibody is purified.
IL-13 is a cytokine involved in regulating inflammatory and immune responses. It down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines, and is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils. IL-13 also regulates several stages of B cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. Structurally, IL-13 closely resembles IL-3, IL-4, IL-5 and GM-CSF.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: IL-13; IL13; Interleukin-13; NC30
Gene Aliases: IL-13; IL13; NC30; P600
UniProt ID: (Human) P35225
Entrez Gene ID: (Human) 3596
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