|Flow Cytometry (Flow)||1 µg/10^6 cells|
|Tested Species reactivity||Mouse|
|Host / Isotype||Rat / IgG1, kappa|
|Immunogen||E. coli-expressed recombinant mouse IL-17|
|Contains||0.1% sodium azide|
|Storage conditions||4° C|
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CTLA-8; CTLA8; Cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated serine esterase 8; IL-17; IL17; interleukin 17; Interleukin-17A
Gene Aliases: Ctla-8; Ctla8; IL-17; IL-17A; Il17; Il17a
UniProt ID: (Mouse) Q62386
Entrez Gene ID: (Mouse) 16171
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.