|Western Blot (WB)||1:500-1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Peptide corresponding to residues C(102) N Y T E A F Q T Q T R P S G G K(118) of human IL-17BR.|
|Storage buffer||PBS with 0.1mg/ml BSA|
|Contains||0.02% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
Suggested positive control: Hela whole cell extract, HeLa cell lysate.
Recently, a number of cytokines belonging to the interleukin (IL)-17 family have been identified. These are IL-17B, IL-17C, and IL-17E. Like IL-17, IL-17B, C, and E are able to induce proinflammatory responses but don't bind to the IL-17 receptor suggesting additional IL-17R related receptors might exist. IL-17E induces activation of NF-kB pathway and like IL-17 also induces production of IL-8. IL-17Rh1 mRNA is highly expressed in kidney and liver and at moderate level in small intestine, colon, and brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CRL4; cytokine receptor CRL4; Cytokine receptor-like 4; EVI27; IL-17 receptor B; IL-17 receptor homolog 1; IL-17B receptor; IL-17RB; IL-17Rh1; IL17BR; IL17RH1; interleukin 17 receptor homolog 1; interleukin 17B receptor; Interleukin-17 receptor B; Interleukin-17B receptor; MGC5245
Gene Aliases: CRL4; EVI27; IL17BR; IL17RB; IL17RH1; UNQ2501/PRO19612
UniProt ID: (Human) Q9NRM6
Entrez Gene ID: (Human) 55540
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