|ELISA (ELISA)||5-10 µg/mL|
|Western Blot (WB)||5-10 µg/mL|
|Tested Species reactivity||Human|
|Host / Isotype||Sheep / IgG|
|Immunogen||Recombinant human IL-1Ra|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA1-75184 specifically detects IL-1R agonist.
PA1-75184 has been successfully used in ELISA and Western blot applications.
The PA1-75184 immunogen is Recombinant IL-1Ra.
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DIRA; ICIL-1RA; IL-1ra3; IL-1RN; IL1 inhibitor; IL1F3; IL1RA; Interleukin-1 receptor antagonist protein; intracellular IL-1 receptor antagonist type II; intracellular interleukin-1 receptor antagonist (icIL-1ra); MGC10430; MVCD4; type II interleukin-1 receptor antagonist
Gene Aliases: DIRA; ICIL-1RA; IL-1ra; IL-1ra3; IL-1RN; IL1F3; IL1RA; IL1RN; IRAP; MVCD4
UniProt ID: (Human) P18510
Entrez Gene ID: (Human) 3557
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