|Flow Cytometry (Flow)||0.5 ug/10^6 cells|
|Immunohistochemistry (Frozen) (IHC (F))||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||Assay Dependent|
|Tested Species reactivity||Rat|
|Host / Isotype||Mouse / IgG1|
|Immunogen||T blasts from a mixed lymphocyte reaction between purified CD4 positive T cells and irradiated spleens.|
|Storage buffer||PBS with 4-5mg/ml BSA|
|Contains||0.02% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
MA5-17491 targets CD25/IL-2R alpha chain in FACS, IHC (F), and IHC (P) applications and shows reactivity with Rat samples.
The MA5-17491 immunogen is t blasts from a mixed lymphocyte reaction between purified CD4 positive T cells and irradiated spleens.
The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD25; IL-2 receptor alpha subunit; IL-2 receptor subunit alpha; IL-2-RA; IL-2R alpha chain; IL-2R subunit alpha; IL2 RA antibody; IL2-RA; Il2ra antibody; Interleukin 2 receptor alpha chain antibody; interleukin 2 receptor, alpha chain; interleukin-2 receptor alpha chain; Interleukin-2 receptor subunit alpha; TAC antigen antibody
Gene Aliases: Il2ra; IL2RAC
UniProt ID: (Rat) P26897
Entrez Gene ID: (Rat) 25704
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