|Flow Cytometry (Flow)||0.5 ug/10^6 cells|
|Flow Cytometry (Flow)||See 9 publications below|
|Miscellaneous PubMed (MISC)||See 15 publications below|
|Immunohistochemistry (Frozen) (IHC (F))||See 1 publications below|
|Tested Species reactivity||Mouse|
|Published species reactivity||Mouse|
|Host / Isotype||Rat / IgG1|
|Immunogen||B6.1 CTL Cell line|
|Storage buffer||PBS with 4-5mg/ml BSA|
|Contains||0.02% sodium azide|
|Storage conditions||4° C, do not freeze|
MA5-17818 targets CD25/IL-2R alpha chain in FACS applications and shows reactivity with Mouse samples.
The MA5-17818 immunogen is b6.1 CTL Cell line.
The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD25; IL-2 receptor subunit alpha; IL-2-RA; IL-2R alpha chain; IL-2R subunit alpha; IL2 RA antibody; IL2-RA; Il2ra antibody; Interleukin 2 receptor alpha chain antibody; Interleukin-2 receptor subunit alpha; p55; p55 chain; TAC antigen antibody
Gene Aliases: CD25; Il2r; Il2ra; Ly-43
UniProt ID: (Mouse) P01590
Entrez Gene ID: (Mouse) 16184
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