|Western Blot (WB)||1-2 ug/ml|
|Tested Species reactivity||Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein corresponding to amino acids 21–95 of mouse Interleukin 4|
|Contains||0.09% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
This antibody is predicted to react with rat, non-human primate and rabbit based on sequence homology.
ABfinity™ recombinant antibodies are rabbit monoclonal antibodies, unmatched for producing superior results. ABfinity™ antibodies are developed by immunizing animals, screening for functionality, cloning the immunogen-specific antibody genes into high-level mammalian expression vectors, produced on a large scale and purified with Protein A.
ABfinity™ oligoclonal antibodies comprise a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds—the sensitivity of a polyclonal antibody with the specificity of a monoclonal, all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody—recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets when compared with monoclonal antibodies—an oligoclonal antibody has a known mixture of light and heavy chains. This exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production.
Intact IgG appears on a non-reducing gel as ~150 kDa band and upon reduction generating a ~25 kDa light chain band and a ~50 kDa heavy chain.
Interleukin-4 is a pleiotropic cytokine responsible for differentiation of T-cells. IL-4 has been found to have the broadest range of actions. It has been found to bind to IL-13 which may result in overlapping functions between IL-4 and IL-13. A signal transducer STAT6 is known to play a important role in arbitrating immune regulatory signal of IL-4. It is found as a cluster with other Interleukins on the q arm of chromosome 5.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: B cell growth factor 1; B-cell growth factor 1; B-cell IgG differentiation factor; B-cell stimulatory factor 1; B_cell stimulatory factor 1; binetrakin; BSF-1; IGG1 induction factor; IL-4; Interleukin-4; Lymphocyte stimulatory factor 1; pitrakinra
Gene Aliases: BSF-1; Il-4; Il4
UniProt ID: (Mouse) P07750
Entrez Gene ID: (Mouse) 16189
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