|Western Blot (WB)||Assay Dependent|
|ELISA (ELISA)||See 16 publications below|
|Immunohistochemistry (Frozen) (IHC (F))||See 1 publications below|
|Flow Cytometry (Flow)||See 4 publications below|
|Blocking Assay (BLOCK)||See 1 publications below|
|Immunocytochemistry (ICC)||See 1 publications below|
|Immunohistochemistry (IHC)||See 1 publications below|
|Tested Species reactivity||Mouse|
|Published species reactivity||Rat , Mouse|
|Host / Isotype||Rat / IgG1|
|Immunogen||Recombinant mouse IL-4|
MM450D targets IL-4 in WB applications and shows reactivity with mouse samples.
The MM450D immunogen is recombinant mouse IL-4.
MM450D detects IL-4 which has a predicted molecular weight of approximately 14 kDa.
This antibody is produced by injecting Rat IgG secreting hybridoma cells into the peritoneum of mice. The resulting ascites is collected from the mice and the antibody is purified.
The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: B-cell growth factor 1; B-cell IgG differentiation factor; B-cell stimulatory factor 1; BSF-1; IGG1 induction factor; IL-4; Interleukin-4; Lymphocyte stimulatory factor 1
Gene Aliases: BSF-1; Il-4; Il4
UniProt ID: (Mouse) P07750
Entrez Gene ID: (Mouse) 16189
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