|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 61 and 310 of Human IMPDH1|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-27792 targets IMPDH1 in WB applications and shows reactivity with Human samples.
The PA5-27792 immunogen is recombinant fragment corresponding to a region within amino acids 61 and 310 of Human IMPDH1.
The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: IMP (inosine 5'-monophosphate) dehydrogenase 1; IMP (inosine monophosphate) dehydrogenase 1; IMP dehydrogenase 1; IMPD; IMPD 1; IMPD1; IMPDH 1; IMPDH-I; Inosine-5'-monophosphate dehydrogenase 1; LCA11; RP10; sWSS2608
Gene Aliases: IMPD; IMPD1; IMPDH-I; IMPDH1; LCA11; RP10; sWSS2608
UniProt ID: (Human) P20839
Entrez Gene ID: (Human) 3614
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.