|Inhibition Assays (IA)||10nM|
|Blocking Assay (BLOCK)||See 3 publications below|
|Western Blot (WB)||See 1 publications below|
|Tested Species reactivity||Bovine, Human, Sheep, Pig|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||IM-9 lymphocytes followed by purified insulin receptor|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage conditions||4° C|
MA5-13773 targets Insulin Receptor alpha in IA applications and shows reactivity with Bovine, Human, Ovine, and Porcine samples.
The MA5-13773 immunogen is iM-9 lymphocytes followed by purified insulin receptor.
The human insulin receptor is a heterotetrameric membrane glycoprotein consisting of disulfide-linked subunits in a beta-alpha-alpha-beta configuration. The beta-subunit (95kDa) possesses a single transmembrane domain with tyrosine kinase activity, whereas the alpha-subunit (135kDa) is completely extracellular.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD220; HHF5; Insulin receptor; IR; IR alpha
Gene Aliases: BOS_7553; CD220; HHF5; INSR; ir; ir-A
UniProt ID: (Human) P06213
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