|ELISA (ELISA)||Assay Dependent|
|Radioimmune Assays (RIA)||Assay Dependent|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Contains||0.09% sodium azide|
|Storage conditions||4°C or -20°C if preferred|
This product has an Affinity of 10^8-10^9 L/mole.
Insulin-like growth factor 1 (IGF-1) is involved in regulation of neuronal growth and development in central and peripheral nervous system. It is known to protect neurons against cell death induced by amyloidogenic derivatives, glucose or serum deprivation through pathways involving AKT kinase and transcription factor FKHRL1 phosphorylation. Activation of the insulin-like growth factor system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like breast and thyroid cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: IGF-I; IGF-I, IGF1A, IGFI,IGF-IA; IGF-IB; insulin-like growth factor 1; insulin-like growth factor 1 (somatomedin C); Insulin-like growth factor I; insulin-like growth factor IA; insulin-like growth factor IB; Mechano growth factor; MGF; Somatomedin-C
Gene Aliases: IBP1; IGF-I; IGF1; IGFI; MGF
UniProt ID: (Human) P05019
Entrez Gene ID: (Human) 3479
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.