|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 224 of Human IRE1 alpha|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-29800 targets IRE1 alpha in WB applications and shows reactivity with Human samples.
The PA5-29800 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 224 of Human IRE1 alpha.
The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Endoplasmic reticulum-to-nucleus signaling 1; ER to nucleus signalling 1; ERN1; hIRE1p; inositol-requiring 1; inositol-requiring enzyme 1; Inositol-requiring protein 1; IRE1; Ire1-alpha; IRE1a; IRE1P; protein kinase/endoribonuclease; Serine/threonine-protein kinase/endoribonuclease IRE1
Gene Aliases: ERN1; hIRE1p; IRE1; IRE1a; IRE1P
UniProt ID: (Human) O75460
Entrez Gene ID: (Human) 2081
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