|Western Blot (WB)||0.2-0.6 µg/ml|
|Tested Species reactivity||Mouse|
|Host / Isotype||Goat / IgG|
|Immunogen||Peptide with sequence C-DRGTKERKEAKEVRD, from the internal region of mouse Irs4 (aa633-647)|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
This antibody is predicted to react with rat based on sequence homology.
IRS4 encodes the insulin receptor substrate 4, a cytoplasmic protein that contains many potential tyrosine and serine/threonine phosphorylation sites. Tyrosine-phosphorylated IRS4 protein has been shown to associate with cytoplasmic signalling molecules that contain SH2 domains. The IRS4 protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Insulin receptor substrate 4; IRS-4; Phosphoprotein of 160 kDa; pp160; RP23-415G1.3
Gene Aliases: IRS-4; Irs4
UniProt ID: (Mouse) Q9Z0Y7
Entrez Gene ID: (Mouse) 16370
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