|Flow Cytometry (Flow)||1:25-1:200 (10 µl for 10^6 cells in 100 µl)|
|Immunohistochemistry (Paraffin) (IHC (P))||1:25-1:200|
|Immunohistochemistry - Free Floating (IHC (Free))||See 1 publications below|
|Immunocytochemistry (ICC)||See 1 publications below|
|Flow Cytometry (Flow)||See 1 publications below|
|Immunohistochemistry (IHC)||See 1 publications below|
|Miscellaneous PubMed (MISC)||See 1 publications below|
|Immunoprecipitation (IP)||See 1 publications below|
|Tested Species reactivity||Rat|
|Published species reactivity||Rat|
|Host / Isotype||Mouse / IgG2a|
|Contains||0.01% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
MA1-21591 detects CD11b/c in rat samples.
MA1-21591 has been successfully used in ELISA, FACS and immunohistochemistry (paraffin) procedures.
The MA1-21591 immunogen is rat macrophages.
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
CD11b, also known as integrin alpha-M (ITGAM) or integrin alpha-X (ITGAX), is a 165 kDa adhesion molecule that associates non-covalently with integrin beta-2 (CD18). The CD11b/CD18 heterodimeric complex is also known as integrin alpha-M beta-2, Mac-1, and CR3 (complement receptor 3). CD11b is expressed on the surface of monocytes/macrophages, granulocytes, activated lymphocytes, a subset of NK cells, a subset of dendritic cells, and microglia in the brain. CD11b/CD18 functions as the receptor for ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), CD14, CD50, CD23, heparin, iC3b, fibrinogen, and Factor X. These adhesions are critical for cell-cell and cell-matrix interactions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD11B; CD11bc; CR3A; integrin alpha-M; integrin alpha-X; integrin, alpha X; Itgam; Itgax; MAC-1; MAC1A; MGC117044; MO1A; SLEB6
Gene Aliases: Cd11b; RGD1561123
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