|Flow Cytometry (Flow)||1:1-1:20 (10 µl for 10^6 cells in 100 µl)|
|Immunohistochemistry (Frozen) (IHC (F))||Neat-1:20|
|Immunohistochemistry (Paraffin) (IHC (P))||Neat-1:20|
|Immunocytochemistry (ICC)||See 1 publications below|
|Tested Species reactivity||Rat|
|Published species reactivity||Rat|
|Host / Isotype||Mouse / IgG2a|
|Contains||0.01% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
MA1-21592 detects CD11b/c (FITC) in Rat samples.
MA1-21592 has been successfully used in FACS and Immunohistochemistry (Paraffin) procedures.
MA1-21592 immunogen corresponds to rat macrophages.
For extended storage, store at -20°C, avoiding freeze/thaw cycles.
CD11b, also known as integrin alpha-M (ITGAM) or integrin alpha-X (ITGAX), is a 165 kDa adhesion molecule that associates non-covalently with integrin beta-2 (CD18). The CD11b/CD18 heterodimeric complex is also known as integrin alpha-M beta-2, Mac-1, and CR3 (complement receptor 3). CD11b is expressed on the surface of monocytes/macrophages, granulocytes, activated lymphocytes, a subset of NK cells, a subset of dendritic cells, and microglia in the brain. CD11b/CD18 functions as the receptor for ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), CD14, CD50, CD23, heparin, iC3b, fibrinogen, and Factor X. These adhesions are critical for cell-cell and cell-matrix interactions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD11B; CD11bc; CR3A; integrin alpha-M; integrin alpha-X; integrin, alpha X; Itgam; Itgax; MAC-1; MAC1A; MGC117044; MO1A; SLEB6
Gene Aliases: Cd11b; RGD1561123
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