|Flow Cytometry (Flow)||0.1 ug/10^6 cells|
|Tested Species reactivity||Rat|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||Rat Peritoneal Macrophages|
|Contains||0.02% sodium azide|
|Storage conditions||4° C, do not freeze|
MA5-17507 targets CD11b/c in FACS applications and shows reactivity with Rat samples.
The MA5-17507 immunogen is rat Peritoneal Macrophages.
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD11B; CD11bc; CR3A; integrin alpha-M; integrin alpha-X; integrin, alpha X; Itgam; Itgax; MAC-1; MAC1A; MGC117044; MO1A; SLEB6
Gene Aliases: Cd11b; RGD1561123
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