|Immunohistochemistry (Paraffin) (IHC (P))||5 µg/ml|
|Western Blot (WB)||2-4 µg/ml|
|Tested Species reactivity||Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide (87 SEVTGETSLEKNGQEAGP 104) of Ifi204 protein.|
|Storage buffer||PBS with 0.05% BSA|
|Contains||0.05% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
Interferon-activable protein 204 belongs to the HIN-200 family, which contains one DAPIN domain and two HIN-200 domains. It is reported to inhibit transcription of ribosomal RNA and thus acts as a multifunctional regulator of cell proliferation and differentiation. It is reported to act as a transcriptional coactivator of Cbfa1 (Core binding factor alpha-1) and enhances osteoblast differentiation. It enables skeletal muscle and cardiac myocyte differentiation by sequestering Id proteins in the cytosol and promoting their ubiquitination and subsequent degradation. It is also reported that Ifi204 is trancriptionally activated in response to M-CSF and thus involved in macrophage differentiation in myeloid progenitor cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: gamma-inducible gene 204; gamma-inducible protein 16; Ifi-204; Ifi16; interferon; interferon, gamma-inducible gene 204; interferon, gamma-inducible protein 16; Interferon-activable protein 204; Interferon-inducible protein p204; p204
Gene Aliases: Ifi16; Ifi204; p204
UniProt ID: (Mouse) P0DOV2
Entrez Gene ID: (Mouse) 15951
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