|Western Blot (WB)||1:500 - 1:2000|
|Tested Species reactivity||Virus|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified recombinant fragment of Influenza A virus nucleoprotein expressed in E. Coli strain BL21(DE3).|
|Contains||0.03% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
MA5-17101 targets Influenza A virus Nucleoprotein in pep-ELISA and WB applications and shows reactivity with Virus samples.
The MA5-17101 immunogen is purified recombinant fragment of Influenza A virus nucleoprotein expressed in E. Coli strain BL21(DE3).
The nucleoprotein (NP) of Influenza A virus encapsidates the negative strand of the viral RNA and is essential for replicative transcription. It may also be involved in other essential functions throughout the virus life cycle. As well as binding ssRNA, NP is able to self associate to form large oligomeric complexes. NP is able to interact with a variety of other macromolecules of both viral and cellular origins. It binds the PB1 and PB2 subunits of the polymerase and the matrix protein M1. "NP has also been shown to interact with at least four cellular polypeptide families: nuclear import receptors of the importin class, filamentous (F) actin, the nuclear export receptor CRM1 and a DEAD box helicase BAT1/UAP56" (Portela et al 2002).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Influenza nucleoprotein
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.