|Immunohistochemistry (Paraffin) (IHC (P))||0.5-1.0 µg/ml|
|Immunohistochemistry (Paraffin) (IHC (P))||See 1 publications below|
|Immunohistochemistry (IHC)||See 5 publications below|
|Immunocytochemistry (ICC)||See 1 publications below|
|Tested Species reactivity||Human, Pig, Rat|
|Published species reactivity||Rat , Mouse , Human|
|Host / Isotype||Mouse / IgG1, kappa|
|Clone||INS04 + INS05|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage conditions||4° C|
MA5-12042 targets Insulin (INS04 + INS05) in IHC (P) applications and shows reactivity with Human, Porcine, and Rat samples.
The MA5-12042 immunogen is insulin protein.
Insulin is a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell of islets of Langerhans and tumor (insulinoma) marker.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ILPR; Ins1; Ins2; Insulin; Insulin-1; Insulin-2; IRDN; preproinsulin; proinsulin
Gene Aliases: IDDM; IDDM1; IDDM2; ILPR; INS; Ins-1; Ins-2; Ins1; Ins2; IRDN; MODY10
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