|Flow Cytometry (Flow)||1:50-1:100|
|Immunohistochemistry (Frozen) (IHC (F))||Assay Dependent|
|Immunoprecipitation (IP)||Assay Dependent|
|Tested Species reactivity||Mouse|
|Host / Isotype||Rat / IgG1|
|Immunogen||Purified murine platelets|
|Contains||0.09% sodium azide|
|Storage conditions||4°C or -20°C if preferred|
For FACS analysis, use 10ul of the suggested working dilution to label 1x10^6 cells in 100ul.
CD41 (platelet glycoprotein IIb) is composed of two subunits, 120kDa alpha and 23kDa beta, that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: alpha IIb; alpha subunit; BDPLT2; CD41; CD41B; GP IIb; GP2B; GPalpha IIb; GPIIb; GTA; HPA3; Integrin alpha-IIb; ITGA2B; platelet fibrinogen receptor; platelet glycoprotein IIb of IIb/II Ia complex; Platelet membrane glycoprotein IIb; platelet-specific antigen BAK
Gene Aliases: AI172977; alphaIIb; CD41; CD41B; GpIIb; Itga2b
UniProt ID: (Mouse) Q9QUM0
Entrez Gene ID: (Mouse) 16399
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.